Koi with KHV often show gill mottling with red and white patches
Kippo: Oral anti-Koi herpes virus vaccine developed in Mie
A Mie University research team...has developed for the first time in the world an oral anti-Koi (carp) herpes virus (KHV) vaccine. The team gave Koi feed incorporating a KHV Liposome vaccine mixed by an artificially made Liposome after inactivating KHV's infection power. The oral administration of vaccine has boosted Koi's ability to create antibodies five to 25 times from usual levels. Compared with conventional methods of injecting vaccines, the newly developed method requires less time and work, and does not hurt Koi. The outbreak of the KHV disease was first reported in Israel in 1998. The disease has since spread widely in the world. In Japan, it broke out in Kasumigaura, Ibaraki Prefecture, in November 2003 and prevailed nationwide, resulting in massive deaths of carp in the absence of effective ways of treatment.
